|
White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Wheezing
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
Serum levels of Tumor Necrosis Factor-α (TNF-α), Monocyte chemotactic protein-1 (MCP-1), Vascular endothelial growth factor (VEGF), Epidermal growth factor (EGF), forced expiratory volume-one second (FEV<sub>1</sub>) and respiratory symptoms including; Chest wheeze (CW), night wheeze (NW), night cough (NC) and cough and wheeze during exercise (ECW) were assessed at the baseline (step 0), one and two months after starting treatment (step I and II, respectively).
|
30961947 |
2019 |
|
Wasting
|
0.010 |
Biomarker
|
disease |
BEFREE |
When EGF is offside, magnesium is wasted.
|
17671646 |
2007 |
|
Walker-Warburg congenital muscular dystrophy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Using the antibody, we show that mutations of GTDC2 identified in Walker-Warburg syndrome and alanine-substitution of conserved residues between GTDC2 and EGF domain O-GlcNAc transferase resulted in decreased glycosylation.
|
24041696 |
2013 |
|
Virus Diseases
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Impact of epidermal growth factor single-nucleotide polymorphism on recurrence of hepatocellular carcinoma after hepatectomy in patients with chronic hepatitis C virus infection.
|
24703510 |
2014 |
|
Virus Diseases
|
0.020 |
Biomarker
|
group |
BEFREE |
Specific patterns of EGF binding and of immunoreactive receptors characterize normal growth and differentiation and these are altered during the abnormal growth and differentiation associated with diseases such as psoriasis, viral infections, neoplasms, and paraneoplastic syndromes.
|
2191051 |
1990 |
|
Vesicoureteral Reflux 1
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Following successful VUR repair, urinary EGF levels of VUR children progressively increased only at long term follow-up but without returning to normal levels.
|
28191787 |
2017 |
|
Vesico-Ureteral Reflux
|
0.010 |
Biomarker
|
disease |
BEFREE |
Urinary excretion of EGF and MCP-1 in children with vesicoureteral reflux.
|
28191787 |
2017 |
|
Vertigo
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Venous Thromboembolism
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Compared to healthy controls, Ang-2 was significantly higher (p = .001) while Ang-1 and EGF were significantly lower (p = .001 and p = .004; respectively) in VTE patients compared to healthy subjects.
|
28949256 |
2017 |
|
Venous Thromboembolism
|
0.020 |
GeneticVariation
|
phenotype |
BEFREE |
TM845G-->A (Ala25Thr; lectin region), TM2136T-->C (Ala455Val; EGF(6) region), TM2470C deletion (3'-untranslated region), and 4363A-->G (3'-flanking region) were more common, but were not associated with VTE by genotype or haplotype.
|
15842356 |
2005 |
|
Vasculitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Urinary epidermal growth factor predicts renal prognosis in antineutrophil cytoplasmic antibody-associated vasculitis.
|
29724728 |
2018 |
|
Vascular Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
These results suggest that increased plasma HB-EGF derived from the accumulated fat contributes to the higher incidence of vascular disease in obesity, proposing HB-EGF as an adipocytokine directly linking adipovascular axis.
|
11922634 |
2002 |
|
Uveitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Significant differences in tear levels of those molecules and also EGF were also present depending on the anatomic classification of uveitis.
|
27873479 |
2017 |
|
Uveal melanoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by Gefitinib and Cetuximab triggered antibody-dependent cellular cytotoxicity.
|
23849826 |
2013 |
|
Uveal melanoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
IGF-1 and EGF may have a role in the development and progression of uveal melanoma.
|
20061986 |
2010 |
|
Uveal melanoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Interleukin 6, 8 (IL-6, IL-8, respectively), interferon-inducible protein-10 (IP-10), placental growth factor1 (PIGF1), regulated on activation, normal T Cell expressed and secreted (RANTES), monocyte chemoattractant protein-1 (MCP-1), nerve growth factor-beta (NGF-β), epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), and vascular endothelia growth factor A (VEGF-A) were assessed by multiplex bead assay.In the study group, significantly higher concentrations of IL-6 (P = .006), IL-8 (P = .018), IP-10 (P = .004), RANTES (P = .008), MCP-1 (P = .02), NGF-β (P = .013), EGF (P < .001), PIGF1 (P = .01), bFGF (P = .016), and VEGF (P = .017) were measured, when compared with the control group.Several angiogenic, inflammatory, and chemotactic cytokines are highly expressed in the aqueous humor of the UM eyes, which provides new insights into the pathophysiology of UM and could be potential targets for treatment.
|
30702560 |
2019 |
|
Uterine Fibroids
|
0.070 |
Biomarker
|
group |
BEFREE |
Epidermal growth factor and transforming growth factor-beta in uterine fibroids and myometrium.
|
8575689 |
1995 |
|
Uterine Fibroids
|
0.070 |
AlteredExpression
|
group |
BEFREE |
Epidermal growth factor-containing fibulin-like extracellular matrix protein 1 expression and regulation in uterine leiomyoma.
|
26702771 |
2016 |
|
Uterine Fibroids
|
0.070 |
AlteredExpression
|
group |
BEFREE |
EGF-R overexpression was detected in leiomyosarcomas while a lack of or reduced EGF-R expression was observed in the nonsarcomatous group (LMs, ALMs, and STUMPs) with a highly significant difference.
|
29729689 |
2018 |
|
Uterine Fibroids
|
0.070 |
AlteredExpression
|
group |
BEFREE |
The growth factors with mitogenic activity, such as transforming growth factor-β3, fibroblast growth factor, epidermal growth factor, and insulin-like growth factor-I are elevated in fibroids and may have a role as effectors of the tumor promotion.
|
28875276 |
2017 |
|
Uterine Fibroids
|
0.070 |
Biomarker
|
group |
BEFREE |
The expression of mRNAs encoding EGF and the EGF receptor in myometrial and leiomyoma cultures suggest that EGF may be involved in the autocrine/paracrine regulation of human uterine leiomyomata and myometrial growth.
|
1936340 |
1991 |
|
Uterine Fibroids
|
0.070 |
AlteredExpression
|
group |
BEFREE |
GnRH antagonist Cetrorelix may directly inhibit leiomyoma cell growth by down-regulating proliferation in association with a decrease in EGF mRNA expression and by up-regulating apoptosis in those cells.
|
15536154 |
2005 |
|
Uterine Fibroids
|
0.070 |
Biomarker
|
group |
BEFREE |
EGF effects on DNA synthesis and intracellular signal transduction were studied in cultured SMCs from leiomyoma and its matched myometrium.
|
21821245 |
2011 |
|
Uterine Cervical Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These results also suggest that combined interferon/retinoid therapy may provide an enhanced beneficial effect to reduce cervical tumor size due to the fact that each agent is inhibiting cervical cell proliferation via distinct, but reinforcing, pathways (i.e., IFN gamma reduces E6/E7 expression, RA inhibits the function of the EGF and IGF1 signalling pathways).
|
7544060 |
1995 |